PROBLEM TO BE SOLVED: To provide a useful invention by focusing HDC (L-histidine decarboxylase) of skin epidermis.SOLUTION: A composition containing a component (A) is used by contacting with the skin surface with which a component (B) contacts. A composition contains the component (A) and the component (B), and is used by contacting with the skin surface. The component (A) is one or more kinds selected from the group consisting of proanthocyanidin, and a glycoside, amino acid modification, solvate, and/or salt thereof. The component (B) is one or more kinds selected from an anionic surfactant and an ampholytic surfactant.COPYRIGHT: (C)2016,JPO&INPIT