SULFONIL SEMICARBIDES, CARBONIL SEMICARBIDES, SEMICARBIDES AND UREAS, PHARMACEUTICAL COMPOSITIONS OF THE SAME, AND METHODS FOR TREATING HEMORRAGIC FEVER VIROSIS. INCLUDING ARENAVIROSIS INFECTIONS.
THOMAS R. BAILEY,DENNIS E. HRUBY,DONGCHENG DAI,TOVE BOLKEN
申请号：
BRPI0806920
公开号：
BRPI0806920A2
申请日:
2008.01.16
申请国别(地区):
BR
年份:
2014
代理人:
摘要：
Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel sulfonyl semicarbazides, carbonyl semicarbazides, semicarbazides, ureas and related compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, Pinchinde, and VSV), Filoviridae (ebola and Marburg viruses), Flaviviridae (yellow fever, omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever).
