Manoj K. Sharma,Wendy Benjamin,Sarita Mittal,Ashwin Basarkar,Chakravarthy Nachu Narasimhan,Ramesh S. Kashi,Mohammed Shameem,Soumendu Bhattacharya,William P. Forrest, JR.,Yogita Krishnamachari
申请号：
US16609612
公开号：
US20200147213A1
申请日:
2018.05.01
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention relates to stable formulations of antibodies against human programmed death receptor PD-1, or antigen binding fragments thereof. In some embodiments the formulations of the invention comprise between 5-200 mg/mL anti-PD-1 antibody, or antigen binding fragment thereof. The invention further provides methods for treating various cancers with stable formulations of the invention. In some embodiments of the methods of the invention, the formulations are administered to a subject by intravenous or subcutaneous administration.
