The invention refers to a process for preparing a powder comprising one or more human coagulation factor proteins and a lactic acid polymer, comprising the steps of a) mixing and dispersing a lactic acid polymer with a particle size d50 in the range 0.1 2 µm and the one or more human coagulation factor proteins in water, b) drying the dispersion, c) compressing the dried mass from the dispersion, d) comminuting the compressed dried mass from the dispersion to a powder with a particle size d50 in the range of more than 0.5and up to 5 µm.