The syringe with a needle 1 includes a needle tube 3 having a needle tip 3a that can puncture a living body, a needle holding member 7, and an outer cylinder 6 filled with a medicine. The needle holding member 7 is formed coaxially and integrally with the needle tube 3 by insert molding, has a distal end and a proximal end, and holds the needle tube 3 with the needle tip 3a of the needle tube 3 protruding from the distal end side. The outer cylinder 6 is fixed to the needle holding member 7 by welding. The needle holding member 7 and the outer cylinder 6 are formed of substantially the same material.針付きシリンジ1は、生体に穿刺可能な針先3aを有する針管3と、針保持部材7と、薬剤が充填される外筒6とを備えている。針保持部材7は、インサート成形によって針管3と一体に同軸上に形成されて、先端と基端を有し、先端側から針管3の針先3aを突出させた状態で針管3を保持する。外筒6は、溶着によって針保持部材7と固定される。そして、針保持部材7と外筒6は、実質的に同一の材料によって形成される。