The present disclosure provides inventive cosmetic/dermatological formulations and/or preparations that include mesenchymal stem cells (MSCs), and also provides associated methods for repairing, rejuvenating and/or augmenting skin tissue. The formulations and/or preparations include MSCs that are formulated into creams, lotions, and the like. In one aspect, the MSCs are obtained autogenously. In another aspect, the MSCs are obtained from allogeneic sources. In another aspect, the MSCs may be minimally manipulated. In another aspect, the MSCs may be derived from bone marrow or adipose tissue. In another aspect, the MSCs can be utilized from bone marrow concentrate (BMC) or from adipose stromal vascular fraction (SVF). In another aspect, the MSCs can also be utilized after cell expansion. The associated methods comprise topical application of the cosmetic/dermatological formulations and/or preparations onto skin tissue, resulting in repairing, rejuvenating, and/or augmenting the skin tissue.
