The present invention relates to pyridinyl and pyrazinyl-(aza)indolsulfonamides having GPR17 modulator activity. The compounds have utility in the treatment of a variety of GPR17-associated disorders.本發明是關於具有GPR17調節劑活性之吡啶基及吡基-(氮)吲哚磺醯胺。該等化合物具有治療各種GPR17相關疾病的效用。