Barbera Betancourt, Ariana,Dominguez Horta, Maria del Carmen,Lorenzo Perez, Norailys,Padron Palomares, Gabriel Ramon,Falcon Cama, Viviana,Menendez Valdes, Ivon
申请号：
AU2009335405
公开号：
AU2009335405B2
申请日:
2009.12.29
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The present invention relates to the field of medicine, in particular the use of an APL-type peptide, derived from the human 60 kDa heat-shock protein or analogues thereof, for preparing a pharmaceutical composition for treating Crohn's disease, ulcerative colitis and type 1 diabetes mellitus. Said peptide is biodistributed to the gastrointestinal tract and promotes the induction of apoptosis of activated T-cells of the intestinal lamina propria and of the peripheral blood of patients with Crohn's disease. Furthermore this peptide induces apoptosis of mononuclear cells of patients with type 1 diabetes mellitus.
