A hyperbilirubinemia phototherapy apparatus (10) includes a phototherapy device (12) including illuminators (20) arranged to illuminate a neonate with phototherapy illumination effective to treat hyperbilirubinemia. A urine collector (14) is configured to collect urine excreted by a neonate while being illuminated with phototherapy illumination by the phototherapy device. A sensing device (28) is secured to at least one of the phototherapy device and the urine collector. The sensing device is configured to output a measurement of a target biomarker in urine collected by the urine collector.
