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MULTIPLE BI-SPECIFIC BINDING DOMAIN CONSTRUCTS WITH DIFFERENT EPITOPE BINDING TO TREAT CANCER
专利权人:
Fred Hutchinson Cancer Research Center
发明人:
Christopher Mehlin,Colin Correnti,James Olson,Roland B. Walter,Ashok Bandaranayake,George S. Laszlo
申请号:
US16317782
公开号:
US20190233534A1
申请日:
2017.07.14
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Groups of bi-specific binding domain constructs (BS-BDC) to treat cancer are described. Each BS-BDC in a group targets a cancer antigen epitope and an immune cell activating epitope that is different from the cancer antigen epitope and immune cell activating epitope targeted by another BS-BDC in the group. The different cancer antigen epitopes can be on the same cancer antigen.
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