Rotter, Varda,Oren, Moshe,Tal, Perry,Eizenberger, Shay,Ben-Shimon, Avi
申请号：
AU2017214733
公开号：
AU2017214733A1
申请日:
2017.02.03
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
An isolated peptide is provided. The peptide comprises an amino acid sequence arranged in a space and configuration that allow interaction of the peptide with the DNA Binding Domain (DBD) of p53 through at least one residue of the DBD by which p CAP 250 (SEQ ID NO: 1) binds the DBD, wherein the peptide at least partially reactivates a mutant p53 protein, with the proviso that the peptide is not SEQ ID NO: 9-382.
