DISSOLUTION AIDS FOR ORAL PEPTIDE DELIVERY COMPRISING A BIGUANIDE

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专利权人:

AXCESS LIMITED

发明人:

NEW ROGER R. C.,NEW Roger R. C.

申请号：

SI200731413

公开号：

SI1986678T1

申请日:

2007.02.16

申请国别(地区):

SI

年份:

2014

代理人:

摘要：

A pharmaceutical composition comprising a mixture of: (c) an active macromolecular principle (d) an aromatic alcohol absorption enhancer chosen from propyl gallate, butylated hydroxy toluene (BHT), butylated hydroxy anisole (BHA) and analogues and derivatives thereof, or mixtures thereof and (d) a biguanide or a pharmaceutically acceptable salt thereof, capable of increasing the solubility of the aromatic alcohol absorption enhancer in an aqueous medium, wherein the aromatic alcohol absorption enhancer is present in an amount by weight greater than or equal to that of the active principle.

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