Mukund Mehrotra;Yonghong Song;Shawn M. Bauer;Zhaozhong J. Jia;Qing Xu;Anjali Pandey;Jack W. Rose;Wolin Huang;Chandrasekar Venkataramani
发明人:
Shawn M. Bauer,Zhaozhong J. Jia,Yonghong Song,Qing Xu,Mukund Mehrotra,Jack W. Rose,Wolin Huang,Chandrasekar Venkataramani,Anjali Pandey
申请号：
US12386509
公开号：
US08138339B2
申请日:
2009.04.16
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention is directed to 2-cycloalkylamino-4-arylamino-benzamide compounds of formula I pharmaceutically acceptable salts thereof which are inhibitors of syk and/or JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk and/or JAK kinase activity, and methods to prevent or treat a number of conditions mediated at least in part by syk and/or JAK kinase activity, such as cardiovascular disease, inflammatory disease, autoimmune disease and cell proliferative disorder.
