2-amino-3,5-difluoro-3,6-dimethyl-6-phenyl-3,4,5,6-tetrahydropyridines as BACE1 inhibitors for treating alzheimer's disease

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专利权人:

H. Lundbeck A/S

发明人:

Karsten Juhl,Lena Tagmose,Mauro Marigo

申请号：

US15524479

公开号：

US10059669B2

申请日:

2015.11.09

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention is directed to compounds according to Formula (I) which compounds are inhibitors of the BACE1 enzyme. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders for 5 which the reduction of Aβ deposits is beneficial such as Alzheimer's disease.

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