５-脂氧合酶活化蛋白（ＦＬＡＰ）抑制劑农业专利-农业专业知识服务系统

发明人:: HUTCHINSON, JOHN H.,哈奇森　约翰Ｈ,哈奇森　約翰Ｈ,LI, YIWEI,李逸炜,李逸煒,PRASIT, PETPIBOON PEPPI,普来斯特　皮特皮布　派皮,普來斯特　皮特皮布　派皮,ZUNIC, JASMINE ELEANOR,祖尼克　洁斯敏　依莱诺,祖尼克　潔斯敏　依萊諾,MORAN, MARK,默伦　马克,默倫　馬克,ARRUDA, JEANNIE M.,阿鲁达　洁妮,哈奇森约翰H,哈奇森約翰H,普来斯特皮特皮布派皮,普來斯特皮特皮布派皮,祖尼克洁斯敏依莱诺,祖尼克潔斯敏依萊諾,默伦马克,默倫馬克,阿鲁达洁妮

摘要：: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.本文中所述者為化合物，及含有此種化合物之醫藥組合物，其會調制5-脂氧合酶活化蛋白(FLAP)之活性。亦於本文中所描述者為使用此種FLAP調制劑，單獨與併用其他化合物，以治療呼吸道、心血管及其他白三烯素依賴性或白三烯素所媒介症狀或疾病之方法。