Trans - 4 - {2 - [4 - (2,3-dichlorophenyl) piperazin-1-yl] ethyl} - n, N - DIMETHYLCARBAMOYL - cyclohexylamine in the treatment of negative symptoms of schizophrenia
PITTER, JÁNOS GYÖRGY,SZATMÁRI, BALÁZS,DEBELLE, MARC,NÉMETH, GYÖRGY JÓZSEF,LASZLOVSZKY, ISTVÁN
申请号：
CR20150244
公开号：
CR20150244A
申请日:
2015.05.11
申请国别(地区):
CR
年份:
2015
代理人:
摘要：
The present Invention relates to trans - 4 - {2 - [4 - (2,3-dichlorophenyl) piperazin-1-yl] ethyl} - n, N - DIMETHYLCARBAMOYL - cyclohexylamine and their hydrates, solvates and pharmaceutically acceptable salts, polymorphs, preferably hydrochloride trans - 4 - 2 - {[4 - (2,3-dichlorophenyl) piperazin-1-yl] ethyl} - n,N - cyclohexylamine DIMETHYLCARBAMOYL - for use in the treatment of negative symptoms of Schizophrenia and / or primary predominantly negative symptoms of schizophrenia.La presente invención se refiere a trans-4-{2-[4-(2,3-diclorofenil) -piperazin-1-il]-etil}-N,N-dimetilcarbamoil-ciclohexilamina y a sus hidratos, solvatos, polimorfos y sales farmacéuticamente aceptables, preferentemente al clorhidrato de trans-4-{2- [4-(2,3-diclorofenil)-piperazin-1-il]-etil}-N,N-dimetilcarbamoil-ciclohexilamina para su uso en el tratamiento de los síntomas negativos primarios de la esquizofrenia y/o los síntomas predominantemente negativos de la esquizofrenia.
