The Institute of Cancer Research; Royal Cancer Hospital
发明人:
Lord, Christopher James,Williamson, Chris,Jones, Samuel
申请号:
AU2017205101
公开号:
AU2017205101A1
申请日:
2017.01.06
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention relates to Ataxia-Telangiectasia Mutated and Rad3-related protein kinase (ATR) inhibitors for use in methods of treating BAF-complex deficient cancer. The present invention further provides methods for identifying ATR inhibitors for use in the treatment of BAF complex gene mutant or deficient cancers. Medical uses and methods relating to the treatment of synovial sarcoma using ATR inhibitors are also provided.