BEATTY, Gregory,ENGELS, Boris,IDAMAKANTI, Neeraja,JUNE, Carl H.,LOEW, Andreas,SONG, Huijuan,WU, Qilong
申请号：
HK16112520.6
公开号：
HK1224332A
申请日:
2016.10.31
申请国别(地区):
HK
年份:
2017
代理人:
摘要：
Provided are compositions and methods for treating diseases associated with expression of mesothelin. Also provided are a chimeric antigen receptor(CAR) specific to mesothelin, vectors encoding the same, and recombinant T cells comprising the mesothelin CAR. Further provided are methods of administering a genetically modified T cell expressing a CAR that comprises a mesothelin binding domain.
