ORGAN HUMANIZED MOUSE

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专利权人:

TRANSGENIC INC.

发明人:

YAMAMURA Kenichi,LI Zhenghua

申请号：

US201515736899

公开号：

US2018360006(A1)

申请日:

2015.06.18

申请国别(地区):

美国

年份:

2018

代理人:

摘要：

The present invention provides embryonic stem cells obtained from an embryo of a mouse engineered to replace all or some of domains in the mouse MHC class I molecule H2-D with domains from the human MHC class I molecule HLA-A by culture in the presence of a GSK3 inhibitor and an MEK inhibitor, as well as a mouse which is created with the use of these embryonic stem cells.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/