The present invention is in the field of a life cycle syn— chronization system for nematodes and a method for life cycle synchronization of such nematodes. In particular the present invention relates to an improved filter design for said system and an improved method of operating said filter, such that an efficient and effective synchronization can be established. An example of a nematode is Caenorhabditis elegans (C. el— egans). C. elegans is a small, free—living soil nematode (roundworm) that lives in many parts of the world. It feeds mainly on microbes, primarily bacteria. C. elegans is considered and used as an important model system for biological re— search in many fields including genomics, cell biology, neuro— science and aging.