The invention provides, inter alia, devices and systems adapted for treating Barretts esophagus and associated methods of treatment using the devices. In certain embodiments, the invention provides an ablation catheter and method of use to endoscopically access portions of the human esophagus where undesired growth of epithelium may develop. In some embodiments, the devices and systems include a microwave antenna, an ablation means (such as a microwave ablation means), an expandable basket configured to accommodate an optical inspection system proximate to the ablation means and a radiometer coupled to the antenna, the radiometer being configured to measure, e.g., temperature and or impedance mismatch from the antenna.
