Peter Dove;Suman Rakhit;Sarah Silverman;Jailall Ramnauth;Subhash C. Annedi;Shawn Maddaford
发明人:
Jailall Ramnauth,Subhash C. Annedi,Sarah Silverman,Peter Dove,Shawn Maddaford,Suman Rakhit
申请号:
US12498185
公开号:
US08106043B2
申请日:
2009.07.06
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention features benzothiazines that inhibit nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms, and that have the formula:The NOS inhibitors of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions.