Thomas Voit,Luis Garcia,Jérôme Denard,Fedor Svinartchouk
申请号：
US13636596
公开号：
US20130189225A1
申请日:
2011.03.22
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Methods for increasing the efficiency of target tissue penetration of an adeno-associated virus (AAV) vector in a patient are provided. In some aspects, the methods involve inhibiting the interaction of the serum protein galectin 3 binding protein (G3BP) with AAV vector. Further provided are methods for reducing tissue distribution of a virus or for neutralizing a virus harbored by an organ destined for transplant, or newly transplanted, by administering a composition comprising G3BP.
