您的位置: 首页 > 农业专利 > 详情页

Synthesis of cyclic amidines
专利权人:
Thorsten Neuhaus;Georg Lentzen
发明人:
Georg Lentzen,Thorsten Neuhaus
申请号:
US13003862
公开号:
US08598346B2
申请日:
2009.07.16
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention relates to an innovative method for synthesis of cyclic amidines. The synthesis starts from a β-, γ- or δ-lactone which is twofold brominated. After esterification of the carboxyl function, the bromine atoms are nucleophilically substituted and the corresponding diamino compound is obtained. The ring closure to the cyclic amidine is accomplished subsequently by reaction with orthoester, imidate or thioimidate. Owing to interposing additional steps for recovery of the diamino compound in enantiomerically pure form, the enantiomers of the cyclic amidines can be stereoselectively synthesized.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充