ROBERT MURRAY MCKINNELL,ERIK FENSTER,TOM M. LAM,JERRY NZEREM,MARTA DABROS,VENKAT R. THALLADI,MIROSLAV RAPTA
申请号:
US16456179
公开号:
US20190315724A1
申请日:
2019.06.28
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention provides compounds of formula (I):or a pharmaceutically-acceptable salt thereof, wherein the variables are defined in the specification, that are inhibitors of JAK kinases, particularly JAK3. The invention also provides crystalline forms, pharmaceutical compositions comprising such compounds, methods of using such compounds to treat gastrointestinal and other inflammatory diseases, and processes and intermediates useful for preparing such compounds.