Disinfectant and detergent composition comprises a quaternary ammonium salt and a nonionic surfactant comprising 10C polyethoxylated alcohol. Disinfectant and detergent composition comprises a quaternary ammonium salt and a nonionic surfactant comprising 10C polyethoxylated alcohol of formula (C 10H 21O(CH 2CH 2O) jH). j : 4-12, preferably 4.6 or 8, where j is a degree of ethoxylation. An independent claim is included for disinfecting at least one equipment for medical use, comprising soaking the equipment in an aqueous solution of the composition and optionally rinsing with water.La présente invention concerne une composition désinfectante et détergente comprenant un sel d'ammonium quaternaire et un tensioactif non-ionique, et caractérisée en ce que le tensioactif non-ionique est un alcool en C10 polyéthoxylé de formule C10H21O(CH2CH2O)JH (C10EJ) dans laquelle le degré d'éthoxylation j est de 4 à 12.