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METHODS AND COMPOSITIONS FOR THE TREATMENT OF RETINOPATHY AND OTHER OCULAR DISEASES
专利权人:
Lankenau Institute for Medical Research
发明人:
Alexander J. Muller,Arturo Bravo-Nuevo,Arpita Mondal,Courtney Smith,Hollie E. Flick
申请号:
US16739948
公开号:
US20200147046A1
申请日:
2020.01.10
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Compositions and methods for the treatment of ocular diseases are disclosed. In accordance with one aspect of the instant invention, methods for treating, inhibiting (e.g., reducing), and/or preventing an ocular disease in a subject are provided. The methods comprise the administration of at least one inhibitor of the induction or activity of tryptophan degradation and/or of the downstream pathways that respond to this process. In a particular embodiment, the methods comprise the administration of an inhibitor of IDO1.
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