РЭЙ Диего Ариэл (US),ДЕФОРЕСТ Николь (US),КОКС Хизер (US),ШУКЛА Сони (US)
申请号：
RU2015143713
公开号：
RU2015143713A
申请日:
2014.03.13
申请国别(地区):
RU
年份:
2017
代理人:
摘要：
Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non-replicative transduction particles as reporter molecules.
