The present invention relates to a pharmaceutical formulation which is particularly suitable for the prevention of overdose after coincidental or deliberate simultaneous administration of a plurality of formulations comprising a pharmacologically active ingredient in total over the therapeutic dose of the pharmacologically active ingredient contained therein Which is useful.本発明は、医薬製剤であって、そこに含まれる薬理活性成分の、全体で治療用量を超える薬理活性成分を含む複数の製剤の偶然のもしくは意図的な同時投与後の過剰摂取の予防に特に有用である、医薬製剤に関する。