Solid drug form of N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(4-(dimethylamino)phenyl)cyclopentyl) methyl)urea hydrochloride and compositions, methods and kits related thereto
Hunt III, Stephen Warren,Phillips, Martin Douglas,Matunas, Robert,Chen, Herman,Betancourt, Aimesther,Uzarama, Charles,Thibert, Roch
申请号:
AU2015320358
公开号:
AU2015320358A1
申请日:
2015.09.25
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
A novel solid drug form of N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(4-(dimethylamino)phenyl)cyclopentyl)methyl)urea hydrochloride (also referred to "ATR-101") suitable for oral dosing, and to compositions, methods and kits relating thereto. ATR-101 has particular utility in the treatment of, for example, aberrant adrenocortical cellular activity, including adrenocortical carcinoma (ACC), congenital adrenal hyperplasia (CAH) and Cushing's syndrome.