A self-adhesive film for covering at least a portion of a surface of three-dimensional (3D) objects such as primary medical devices, body tissues, or anatomical structures is described. When wrapped around a three-dimensional object a consistent adhesive bond between the overlapping layers of the self-adhesive film is created, independent of the substrate material of the 3D object surface. The self-adhesive film is capable of delivering actives, such as antimicrobials, drugs, and other biologically active agents to the 3D object, and also in the vicinity of the 3D object and/or adjacent tissue. Various self-adhesive film designs and methods for delivering one or multiple active agents with various controlled release modes, are described.
