Among various methods, systems, and apparatuses, a number of methods are provided for forming a 3D conformance model of a particular portion of a subjects anatomy using 3D digitized imaging data and a rapid prototyping technique. One such a method includes distinguishing at least one particular structural feature associated with the exterior of the particular portion from at least one particular structural feature associated with the interior of the particular portion. Such a method can include using the conformance model to test suitability of an appliance to participate in performing an intended function that includes penetrating the interior of the particular portion through the exterior of the particular portion.
