Lantto, Johan,Andersen, Kim Vilbour,Andersen, Peter Sejer,Strandh, Magnus,Koefoed, Klaus,Nielsen, Lars Sogaard,Pedersen, Mikkel Wandahl,Jacobsen, Helle,Kragh, Michael,Kjaer, Ida,Poulsen, Thomas Tuxen
申请号:
AU2013255537
公开号:
AU2013255537B2
申请日:
2013.05.02
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The invention relates to humanized recombinant antibodies targeting the EGFR family receptors EGFR, HER2 and HER3, compositions comprising at least one humanized anti-EGFR antibody, at least one humanized anti-HER2 antibody and at least one humanized anti-HER3 antibody, and use of the antibody compositions for treatment of cancer. The invention also relates to the use of antibodies targeting multiple EGFR-family receptors to treat cancer (e.g., pancreatic cancer) and cancer that has acquired resistance to previous therapies.