The United States of America as represented by The Secretary of Agriculture;Merial Limited
发明人:
Maki, Joanne L.,Fry, Tricia Lynn,Hurley, Jerome Cornelius,Miller, Lowell Allen
申请号:
AU2012245395
公开号:
AU2012245395A1
申请日:
2012.04.20
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention relates to adjuvanted recombinant anti-rabies vaccines and the oral administration of such vaccines to raccoons and other wildlife. Advantageously, the anti-rabies vaccine may comprise a recombinant vaccinia virus containing a rabies glycoprotein gene. The invention encompasses methods of vaccinating raccoons and other wildlife by administration of an anti-rabies vaccines which may comprise a recombinant vaccinia virus containing a rabies glycoprotein gene, in combination with an adjuvant which increases both vaccine viscosity and efficacy. The invention provides effective oral recombinant vaccines used in oral rabies vaccination (ORV) programs for wildlife, effective at protecting raccoons, gray foxes, coyotes, and other animals.