A spot-on pesticide composition for animals, specifically mammals, including dogs and cats, which composition comprises a combination of active components, including fipronil and a pyrethroid, and optionally an insect growth regulator, in doses and proportions which are parasiticidally effective against a variety of insects and pests, and in a formulation which is convenient for local application to the animal's skin, preferably localized over a small surface area.フィプロニル、ピレスロイド及び所望により昆虫成長制御剤の組合せを、種々の昆虫及び害虫に対して寄生虫駆除効果がある用量及び割合で、並びに動物の皮膚への局所的な塗布のために有用な、好ましくは小さな表面積に局所化された剤形で含有する、動物、特にイヌ及びネコを含む哺乳動物用の局所組成物。