OLSON, Richard E.,CACACE, Angela M.,HAGEDORN, Peter,HØG, Anja Mølhart,JENSEN, Marianne Lerbech,NIELSEN, Niels Fisker,LI, Dong,BROWN, Jeffrey M.,MERCER, Stephen E.
申请号：
PE0013232017
公开号：
PE17662017A1
申请日:
2016.02.04
申请国别(地区):
PE
年份:
2017
代理人:
摘要：
The present Invention relates to compounds of oligomers from 10 to 50 nucleotides in length, which was hybridized to Tau mRNA in a cell, which leads to a lower expression of Tau Protein. Reducing the expression of Tau Protein is beneficial for the treatment of certain Medical disorders, for example, a Neurological DisorderLa presente invencion se refiere a compuestos de oligomeros de 10 a 50 nucleotidos de longitud, que se hibridan a ARNm Tau en una celula, lo que conduce a una expresion menor de la proteina Tau. La reduccion de la expresion de la proteina Tau es beneficiosa para el tratamiento de ciertos trastornos medicos, por ejemplo, un trastorno neurologico
