Methods of ameliorating, treating, or reducing post-dialysis washout or hangover comprising administering, near the end of or subsequent to a dialysis session, one or more or a group of amino acids and/or their hydroxy or keto analogs. The group of amino acids may be one or more members selected from the group consisting of histidine, alanine, isoleucine, arginine, leucine, asparagine, lysine, aspartic acid, methionine, cysteine, phenylalanine, glutamic acid, threonine, glutamine, tryptophan, glycine, valine, pyrrolysine, proline, selenocysteine, serine, and tyrosine, or their keto or hydroxy analogs and mixtures thereof.
