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COMPOUNDS WEAKENING SAICAR SYNTHETASE ACTIVITY AND APPLICATIONS
专利权人:
LTD.;GENEHEAL BIOTECHNOLOGY CO.
发明人:
Wuguang PAN,Wei ZHU
申请号:
US16334256
公开号:
US20190209499A1
申请日:
2017.09.26
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided are compounds reducing SAICAR accumulation, and applications. On the basis of existing protein structure data and small molecule structure data, calculations and analysis are performed using software to screen and obtain compounds capable of effectively interfering with PAICS activity, reducing SAICAR synthesis, and ultimately reducing SAICAR accumulation, in order to achieve the goal of treating or improving ADSL deficiency. A better effect in the treatment or improvement of ADSL deficiency is expected from the joint use of at least two of the described compounds.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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