Raphaël Darteil,Geneviève Cordonnier,Brozek Brozek,Emilie Praca,Fouad Ben Sudrik
申请号：
US15759484
公开号：
US20180265924A1
申请日:
2016.09.14
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention relates to a method for the diagnosis of non-alcoholic steatohepatitis (NASH), for determining the activity, the stage, or the severity of NASH or for classifying a subject as a potential receiver or non receiver of a treatment of NASH using circulating miRNAs and other blood circulating markers of liver damage, e.g. alpha 2 macroglobulin, HbA1c, N-terminal pro-peptide of collagen type III, miR-34 and miR-200. It also relates to a kit for implementing the method of the invention, and the compounds for use in a method for the treatment of NASH, wherein the subject to be treated is identified, evaluated or classified according to the method of the invention.
