Markus KALKUM,Yoko FUJITA-YAMAGUCHI,Karine BAGRAMYAN,Teresa B. HONG,Sarah SHUCK
申请号:
US16165725
公开号:
US20190233479A1
申请日:
2018.10.19
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Disclosed herein are a recombinant Streptomyces S27S5 hemagglutinin (SHA), and homologues thereof, and a fusion protein of a fluorescent protein (such as GFP and mCherry1) and SHA or a homologue thereof, which specifically bind to carbohydrates, including oligomeric sugars that terminate in L-rhamnose or D-galactose. The SHA, SHA homologues, and fusion proteins can be used to detect a variety of microorganisms or cancer or tumor antigens.