THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH;THE SCRIPPS RESEARCH INSTITUTE
发明人:
SHEN, WEIJUN,YANG, PENGYU,ZOU, HUAFEI,SCHULTZ, PETER G.
申请号:
CA2933701
公开号:
CA2933701A1
申请日:
2014.12.17
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Methods and compositions are provided for extending the half-life of a therapeutic agent. A modified therapeutic agent (mTA) comprises a therapeutic agent, a staple, and a half-life extending molecule. The mTAs disclosed herein may be used to treat a disease or a condition in a subject in need thereof.