The invention relates to a device, system and method for optical detection of the condition of a joint. The invention involves: - an optical measurement unit (4, 5) for irradiating a subjects body part comprising at least one joint with light and locally detecting attenuation of the light at the at least one joint and at least one other portion of the body part - a thermographic measurement unit (3) for thermographically imaging the subjects body part comprising the at least one joint - a control unit (9) for controlling the device such that data obtained by one of the optical measurement unit (4, 5) and the thermographic measurement unit (3) is used to calibrate data obtained by the other of the optical measurement unit (4, 5) and the thermographic measurement unit (3).