Robert Costa,Pradip Raychaudhuri,Xinhe Wang,Vladimir Kalinichenko,Michael Major,I-Ching Wang
申请号:
US12871560
公开号:
US08431522B2
申请日:
2010.08.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention provides methods for inhibiting tumor cell proliferation by inhibiting FoxM1B activity, expression, or nuclear localization in a tumor cell. The invention also provides methods for preventing tumor progression in an animal comprising inhibiting FoxM1B activity, expression, or nuclear localization. Furthermore, the invention provides methods for inhibiting tumor cell growth in an animal comprising inhibiting FoxM1B activity, expression, or nuclear localization in tumor cells in the animal.