An apparatus for automatic execution of different treatment operations in connection with staining of tissue specimens on microscope slides, wherein the apparatus (1) comprises an assembly of vessels (4) for receiving different liquids for staining of the tissue specimens, a loading station (2) for microscope slides (28), a conveyor (5) for transfer of carriers with microscope slides from vessel to vessel in accordance with a treatment program, an unloading station (8) for treated microscope slides, and a control unit (18) for controlling the treatment operations in accordance with a data program. The apparatus comprises different levels (I, II) having units for execution of the relevant treatment operations. Thus, a first level (I) comprises the loading station (2) and the assembly of said vessels (4) with the appurtenant conveyor (5), and a second level (II) comprises a station (6) for application of cover glasses on the stained microscope slides (28), a succeeding station (7) for drying of the cover-slipped microscope slides, and the unloading station (8), a means (9) being provided for gripping and transfer of carriers (10) with stained microscope slides from the first level (I) to the cover-slipping station (6) on the second level (II).Linvention concerne un appareil destiné à lexécution automatique de différentes opérations de traitement dans le cadre de la coloration de spécimens de tissus sur des lames porte-objet, lappareil (1) comprenant un ensemble de récipients (4) destinés à recevoir différents liquides pour la coloration des spécimens de tissus, un poste de chargement (2) des lames porte-objet (28), un transporteur (5) pour le transfert de supports avec les lames porte-objet dun récipient à lautre conformément à un programme de traitement, un poste de déchargement (8) des lames porte-objet traitées et un dispositif de commande (18) permettant de commander les opérations de traitement conformément à un programme de données. Lappareil comprend différents