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KOMBINOVANA TERAPIJA ZA LEČENJE MULTIPLE SKLEROZE
专利权人:
FWP IP APS
发明人:
TERWEY, THEIS,RUPP, ROLAND,ANDERSEN, PEDER, M.
申请号:
RSP20180737
公开号:
RS57567B1
申请日:
2013.08.02
申请国别(地区):
RS
年份:
2018
代理人:
摘要:
The present invention relates to a method of treating MS in a human patient in need of such treatment and comprises administering to said patient a combination therapy in a single oral dosage form (e.g. a tablet or capsule) of dimethylfumarate and one agent selected from teriflunomide (or its prodrug leflunomide), fingolimod and laquinimod. This combination is more effective than the single agents alone and/or has reduced side effects and better tolerability than the single agents alone and/or can be given in a reduced frequency. Moreover, the present invention is directed to a pharmaceutical composition suitable for the oral treatment of multiple sclerosis consisting of dimethylfumarate and one agent selected from teriflunomide, fingolimod and laquinimod as active ingredients and one or more pharmaceutically acceptable excipients.
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中国工程科技知识中心
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