A headrest structure is provided and includes a body and two supporting rods. The body includes a covering cushion and an automated external defibrillator (AED). The AED is enclosed by the covering cushion. Each of the supporting rods includes a linking end and a combining end opposite to the linking end, and each of the supporting rods is connected to the body with the linking end so as to support the body. Based on this, the AED is assembled in the body to improve the applicability of the AED, so that patients experiencing cardiac arrest can be treated properly and instantly.