Process for crystalline pemetrexed dipotassium salt

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专利权人:

发明人:

Bhagat Raj Pipal,Venkata Reddy Gayam,Akshay Kant Chaturvedi

申请号：

US15036819

公开号：

US10072012B2

申请日:

2014.11.11

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention provides process for preparing crystalline Pemetrexed dipotassium (I) Form-SP9characterized by X-ray powder diffraction pattern comprising at least 5 characteristic 2θ° peaks selected from the XRPD peak set of 5.0, 12.5, 17.2, 20.8, 22.4, 25.7, 26.9 and 27.9±0.2 2θ°. The invention also provides process for preparing its pharmaceutical composition thereof, which may be useful for anti-cancer treatment.

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