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AGENT THÉRAPEUTIQUE CONTRE LA PNEUMONIE INTERSTITIELLE
专利权人:
LTD.;LTT BIO-PHARMA CO.
发明人:
SHIRAI, KOUJI,KAWASHIMA, TATSUO,KURODA, TOSHIHISA,MIZUSHIMA, YUTAKA,MURAKAMI, MASAHIRO,FUKUZAKI, TOMOHARU
申请号:
EP07850870
公开号:
EP2123295A4
申请日:
2007.12.19
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
A therapeutic agent for interstitial pneumonia is provided which effectively exploits the effect of superoxide dismutase (SOD). The therapeutic composition for interstitial pneumonia contains 10 to 100mg of lecithinized superoxide dismutase represented by the following general formula (I): €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒSOD'(Q-B) m €ƒ€ƒ€ƒ€ƒ€ƒ(I) (wherein SOD' is a residue of superoxide dismutase; Q is a chemical crosslink; B is a residue of lysolecithin having the hydrogen atom of the hydroxyl group at position 2 of its glycerol moiety removed; and m is the average number of lysolecithin molecules bound to one molecule of the superoxide dismutase and is an integer of 1 or greater) and further contains sucrose to give it a stable form suitable for intravenous administration.
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