BUECHLER YING,CHIANG KYLE,DO MINH-HA,LEE DARIN,PIEHL KRISTI,THOMAS MARC,WATKINS JEFFRY D,WU CHI-FANG,MENDLEIN JOHN D
申请号：
IN7868/DELNP/2015
公开号：
IN2015DN07868A
申请日:
2015.09.02
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
The present invention provides histidyl tRNA synthetase and Fc region conjugate polypeptides (HRS Fc conjugates) such as HRS Fc fusion polypeptides compositions comprising the same and methods of using such conjugates and compositions for treating or diagnosing a variety of conditions. The HRS Fc conjugates of the invention have improved controlled release properties stability half life and other pharmacokinetic and biological properties relative to corresponding unmodified HRS polypeptides.
