Xi CHEN,Dean R. DRAGOLI,Pingchen FAN,Yandong LI,Jay P. POWERS,Sreenivas PUNNA,Hiroko TANAKA,Penglie ZHANG
申请号：
US15900405
公开号：
US20180369213A1
申请日:
2018.02.20
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
